The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation Through an Interaction with Rad6

The five-subunit yeast Paf1 Complex (Paf1C) regulates all stages of transcription and is critical for the monoubiquitylation of histone H2B (H2Bub), a modification that broadly influences chromatin structure and eukaryotic transcription. Here we show that the histone modification domain (HMD) of Paf...

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Julkaisussa:Mol Cell
Päätekijät: Van Oss, S. Branden, Shirra, Margaret K., Bataille, Alain R., Wier, Adam D., Yen, Kuangyu, Vinayachandran, Vinesh, Byeon, In-Ja L., Cucinotta, Christine E., Héroux, Annie, Jeon, Jongcheol, Kim, Jaehoon, VanDemark, Andrew P., Pugh, B. Franklin, Arndt, Karen M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131541/
https://ncbi.nlm.nih.gov/pubmed/27840029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.10.008
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