Small region of Rtf1 protein can substitute for complete Paf1 complex in facilitating global histone H2B ubiquitylation in yeast

Histone modifications regulate transcription by RNA polymerase II and maintain a balance between active and repressed chromatin states. The conserved Paf1 complex (Paf1C) promotes specific histone modifications during transcription elongation, but the mechanisms by which it facilitates these marks a...

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Autores principales: Piro, Anthony S., Mayekar, Manasi K., Warner, Marcie H., Davis, Christopher P., Arndt, Karen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390850/
https://ncbi.nlm.nih.gov/pubmed/22699496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116994109
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