T(FH) cells accumulate in mucosal tissues of humanized-DRAG mice and are highly permissive to HIV-1

CD4(+) T follicular helper cells (T(FH)) in germinal centers are required for maturation of B-cells. While the role of T(FH)-cells has been studied in blood and lymph nodes of HIV-1 infected individuals, its role in the mucosal tissues has not been investigated. We show that the gut and female repro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Allam, Atef, Majji, Sai, Peachman, Kristina, Jagodzinski, Linda, Kim, Jiae, Ratto-Kim, Silvia, Wijayalath, Wathsala, Merbah, Melanie, Kim, Jerome H., Michael, Nelson L., Alving, Carl R., Casares, Sofia, Rao, Mangala
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451806/
https://ncbi.nlm.nih.gov/pubmed/26034905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10443
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