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USP7 modulates UV-induced PCNA monoubiquitination by regulating DNA polymerase eta stability
DNA polymerase eta (Polη) plays unique and pivotal functions in several DNA damage-tolerance pathways. Steady-state level of this short-lived protein is tightly controlled by multiple mechanisms including proteolysis. Here, we have identified the deubiquitinating enzyme, ubiquitin-specific protease...
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| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451444/ https://ncbi.nlm.nih.gov/pubmed/25435364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.394 |
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