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Evaluating surrogate endpoints, prognostic markers, and predictive markers — some simple themes

BACKGROUND: A surrogate endpoint is an endpoint observed earlier than the true endpoint (a health outcome) that is used to draw conclusions about the effect of treatment on the unobserved true endpoint. A prognostic marker is a marker for predicting the risk of an event given a control treatment; it...

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Bibliographic Details
Published in:Clin Trials
Main Authors: Baker, Stuart G., Kramer, Barnett S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451440/
https://ncbi.nlm.nih.gov/pubmed/25385934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514557725
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