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Human esophageal myofibroblasts secrete proinflammatory cytokines in response to acid and Toll-like receptor 4 ligands

The pathophysiology of esophageal injury, repair, and inflammation in gastroesophageal reflux-disease (GERD) is complex. Whereas most studies have focused on the epithelial response to GERD injury, we are interested in the stromal response. We hypothesized that subepithelial esophageal myofibroblast...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Main Authors: Gargus, Matthew, Niu, Chao, Vallone, John G., Binkley, Jana, Rubin, Deborah C., Shaker, Anisa
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451324/
https://ncbi.nlm.nih.gov/pubmed/25882613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00333.2014
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