miR-21-mediated decreased neutrophil apoptosis is a determinant of impaired coronary collateral growth in metabolic syndrome

Coronary collateral growth (CCG) is impaired in metabolic syndrome. microRNA-21 (miR-21) is a proproliferative and antiapoptotic miR, which we showed to be elevated in metabolic syndrome. Here we investigate whether impaired CCG in metabolic syndrome involved miR-21-mediated aberrant apoptosis. Norm...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Hutcheson, Rebecca, Terry, Russell, Hutcheson, Brenda, Jadhav, Rashmi, Chaplin, Jennifer, Smith, Erika, Barrington, Robert, Proctor, Spencer D., Rocic, Petra
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Call for Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451306/
https://ncbi.nlm.nih.gov/pubmed/25840830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00654.2014
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