A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest

Sudden cardiac arrest (SCA) is a leading cause of death in the United States. Despite return of spontaneous circulation, patients die due to post-SCA syndrome that includes myocardial dysfunction, brain injury, impaired metabolism, and inflammation. No medications improve SCA survival. Our prior wor...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Li, Jing, Wang, Huashan, Zhong, Qiang, Zhu, Xiangdong, Chen, Sy-Jou, Qian, Yuanyu, Costakis, Jim, Bunney, Gabrielle, Beiser, David G., Leff, Alan R., Lewandowski, E. Douglas, ÓDonnell, J. Michael, Vanden Hoek, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451301/
https://ncbi.nlm.nih.gov/pubmed/25795713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00748.2014
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