Genetic Deletion of NOS3 Increases Lethal Cardiac Dysfunction Following Mouse Cardiac Arrest

STUDY AIMS: Cardiac arrest mortality is significantly affected by failure to obtain return of spontaneous circulation (ROSC) despite cardiopulmonary resuscitation (CPR). Severe myocardial dysfunction and cardiovascular collapse further affects mortality within hours of initial ROSC. Recent work sugg...

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Main Authors: Beiser, David G., Orbelyan, Gerasim A., Inouye, Brendan T., Costakis, James G., Hamann, Kimm J., McNally, Elizabeth M., Hoek, Terry L. Vanden
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018673/
https://ncbi.nlm.nih.gov/pubmed/20951489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resuscitation.2010.08.038
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