Akt1 genetic deficiency limits hypothermia cardioprotection following murine cardiac arrest

Therapeutic hypothermia (TH) cardioprotection has recently been associated with increased Akt signaling in a rat model of cardiac arrest. However, it is not known whether Akt is required for this beneficial effect of TH. We used a mouse model of cardiac arrest demonstrating TH cardioprotection to st...

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Hauptverfasser: Beiser, David G., Wojcik, Kimberly R., Zhao, Danhong, Orbelyan, Gerasim A., Hamann, Kimm J., Vanden Hoek, Terry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886630/
https://ncbi.nlm.nih.gov/pubmed/20363892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00187.2010
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