Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants

Therapeutic hypothermia (TH) is a promising cardioprotective treatment for cardiac arrest and acute myocardial infarction, but its cytoprotective mechanisms remain unknown. In this study, we developed a murine cardiomyocyte model of ischemia-reperfusion injury to better determine the mechanisms of T...

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Autores principales: Shao, Zuo-Hui, Sharp, Willard W., Wojcik, Kimberly R., Li, Chang-Qing, Han, Mei, Chang, Wei-Tien, Ramachandran, Srinivasan, Li, Jing, Hamann, Kimm J., Vanden Hoek, Terry L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886635/
https://ncbi.nlm.nih.gov/pubmed/20382860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00994.2009
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