IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

The most studied biological role of type III interferons (IFNs) has so far been their antiviral activity, but their role in autoimmune and inflammatory diseases remains largely unexplored. Here, we show that treatment with IFN-λ2/IL-28A completely halts and reverses the development of collagen-induc...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451128/
https://ncbi.nlm.nih.gov/pubmed/25941255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140995
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