IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

The most studied biological role of type III interferons (IFNs) has so far been their antiviral activity, but their role in autoimmune and inflammatory diseases remains largely unexplored. Here, we show that treatment with IFN-λ2/IL-28A completely halts and reverses the development of collagen-induc...

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Vydáno v:J Exp Med
Hlavní autoři: Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451128/
https://ncbi.nlm.nih.gov/pubmed/25941255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140995
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