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IFN-λ ‘guts’ neutrophil-mediated inflammation

Interferon-λ (IFN-λ) curbs neutrophil-mediated intestinal inflammation by diminishing the production of reactive oxygen species and subsequent oxidative stress. This regulatory process is unique to IFN-λ and is independent of interferon-induced transcription and translation programs.

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Hemann, Emily A, Schwerk, Johannes, Savan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661971/
https://ncbi.nlm.nih.gov/pubmed/28926532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3834
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