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FcRn: The architect behind the immune and non-immune functions of IgG and albumin

The neonatal Fc receptor (FcRn) belongs to the extensive and functionally divergent family of MHC molecules. Contrary to classical MHC family members, FcRn possesses little diversity and is unable to present antigens. Instead, through its capacity to bind IgG and albumin with high affinity at low pH...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Pyzik, Michal, Rath, Timo, Lencer, Wayne I., Baker, Kristi, Blumberg, Richard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451002/
https://ncbi.nlm.nih.gov/pubmed/25934922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403014
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