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FcRn: The architect behind the immune and non-immune functions of IgG and albumin

The neonatal Fc receptor (FcRn) belongs to the extensive and functionally divergent family of MHC molecules. Contrary to classical MHC family members, FcRn possesses little diversity and is unable to present antigens. Instead, through its capacity to bind IgG and albumin with high affinity at low pH...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Pyzik, Michal, Rath, Timo, Lencer, Wayne I., Baker, Kristi, Blumberg, Richard S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451002/
https://ncbi.nlm.nih.gov/pubmed/25934922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403014
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