FcRn: The architect behind the immune and non-immune functions of IgG and albumin

The neonatal Fc receptor (FcRn) belongs to the extensive and functionally divergent family of MHC molecules. Contrary to classical MHC family members, FcRn possesses little diversity and is unable to present antigens. Instead, through its capacity to bind IgG and albumin with high affinity at low pH...

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Bibliographic Details
Published in:J Immunol
Main Authors: Pyzik, Michal, Rath, Timo, Lencer, Wayne I., Baker, Kristi, Blumberg, Richard S.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451002/
https://ncbi.nlm.nih.gov/pubmed/25934922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403014
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