G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation

BACKGROUND: A novel family of proton-sensing G protein-coupled receptors, including OGR1, GPR4, and TDAG8, was identified to be important for physiological pH homeostasis and inflammation. Thus, we determined the function of proton-sensing OGR1 in the intestinal mucosa. MTEHODS: OGR1 expression in c...

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Publicat a:Inflamm Bowel Dis
Autors principals: de Vallière, Cheryl, Wang, Yu, Eloranta, Jyrki J., Vidal, Solange, Clay, Ieuan, Spalinger, Marianne R., Tcymbarevich, Irina, Terhalle, Anne, Ludwig, Marie-Gabrielle, Suply, Thomas, Fried, Michael, Kullak-Ublick, Gerd A., Frey-Wagner, Isabelle, Scharl, Michael, Seuwen, Klaus, Wagner, Carsten A., Rogler, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2015
Matèries:
Original Basic Science Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450952/
https://ncbi.nlm.nih.gov/pubmed/25856770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000375
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