Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

BACKGROUND & AIMS: A novel family of proton-sensing G-protein–coupled receptors, including ovarian cancer G-protein–coupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a result of anaerobic glucose metabolism through the...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: de Vallière, Cheryl, Cosin-Roger, Jesus, Simmen, Simona, Atrott, Kirstin, Melhem, Hassan, Zeitz, Jonas, Madanchi, Mehdi, Tcymbarevich, Irina, Fried, Michael, Kullak-Ublick, Gerd A., Vavricka, Stephan R., Misselwitz, Benjamin, Seuwen, Klaus, Wagner, Carsten A., Eloranta, Jyrki J., Rogler, Gerhard, Ruiz, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247318/
https://ncbi.nlm.nih.gov/pubmed/28174749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.06.003
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