Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways

Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator induced in many cancers. It is thought to drive tumorigenesis by repressing division, stemness, and/or developmental regulators. Cancers evade immune detection, and diverse immune regulators are perturbed in different tumors. It is uncl...

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Veröffentlicht in:PLoS One
Hauptverfasser: Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Zhao, Michael, Song, Lan, Yu, Tao, Liu, Yu, Liu, Jeffrey C., McCurdy, Sean, Ma, Anqi, Wither, Joan, Jin, Jian, Zacksenhaus, Eldad, Wrana, Jeffrey L., Bremner, Rod
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450877/
https://ncbi.nlm.nih.gov/pubmed/26030458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126466
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