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Activation of peripheral KCNQ channels relieves gout pain

Intense inflammatory pain caused by urate crystals in joints and other tissues is a major symptom of gout. Among therapy drugs that lower urate, benzbromarone (BBR), an inhibitor of urate transporters, is widely used because it is well tolerated and highly effective. We demonstrate that BBR is also...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Zheng, Yueming, Xu, Haiyan, Zhan, Li, Zhou, Xindi, Chen, Xueqin, Gao, Zhaobing
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450870/
https://ncbi.nlm.nih.gov/pubmed/25735002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000122
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