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Activation of peripheral KCNQ channels relieves gout pain

Intense inflammatory pain caused by urate crystals in joints and other tissues is a major symptom of gout. Among therapy drugs that lower urate, benzbromarone (BBR), an inhibitor of urate transporters, is widely used because it is well tolerated and highly effective. We demonstrate that BBR is also...

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Dades bibliogràfiques
Publicat a:Pain
Autors principals: Zheng, Yueming, Xu, Haiyan, Zhan, Li, Zhou, Xindi, Chen, Xueqin, Gao, Zhaobing
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450870/
https://ncbi.nlm.nih.gov/pubmed/25735002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000122
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