SIV Encephalitis Lesions Are Composed of CD163(+) Macrophages Present in the Central Nervous System during Early SIV Infection and SIV-Positive Macrophages Recruited Terminally with AIDS

Macrophage recruitment to the central nervous system (CNS) during AIDS pathogenesis is poorly understood. We measured the accumulation of brain perivascular (CD163(+)) and inflammatory (MAC387(+)) macrophages in SIV-infected monkeys. Monocyte progenitors were 5-bromo-2′-deoxyuridine (BrdU) labeled i...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Nowlin, Brian T., Burdo, Tricia H., Midkiff, Cecily C., Salemi, Marco, Alvarez, Xavier, Williams, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450314/
https://ncbi.nlm.nih.gov/pubmed/25963554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.01.033
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