An internal thioester in a pathogen surface protein mediates covalent host binding

To cause disease and persist in a host, pathogenic and commensal microbes must adhere to tissues. Colonization and infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins. To date, adhesins are only known to bind to host...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Walden, Miriam, Edwards, John M, Dziewulska, Aleksandra M, Bergmann, Rene, Saalbach, Gerhard, Kan, Su-Yin, Miller, Ona K, Weckener, Miriam, Jackson, Rosemary J, Shirran, Sally L, Botting, Catherine H, Florence, Gordon J, Rohde, Manfred, Banfield, Mark J, Schwarz-Linek, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450167/
https://ncbi.nlm.nih.gov/pubmed/26032562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06638
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