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A Highly Unusual Thioester Bond in a Pilus Adhesin Is Required for Efficient Host Cell Interaction

Many bacterial pathogens present adhesins at the tips of long macromolecular filaments known as pili that are often important virulence determinants. Very little is known about how pili presented by Gram-positive pathogens mediate host cell binding. The crystal structure of a pilus adhesin from the...

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Détails bibliographiques
Auteurs principaux: Pointon, Jonathan A., Smith, Wendy D., Saalbach, Gerhard, Crow, Allister, Kehoe, Michael A., Banfield, Mark J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962485/
https://ncbi.nlm.nih.gov/pubmed/20729215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149385
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