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A Highly Unusual Thioester Bond in a Pilus Adhesin Is Required for Efficient Host Cell Interaction

Many bacterial pathogens present adhesins at the tips of long macromolecular filaments known as pili that are often important virulence determinants. Very little is known about how pili presented by Gram-positive pathogens mediate host cell binding. The crystal structure of a pilus adhesin from the...

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Autori principali: Pointon, Jonathan A., Smith, Wendy D., Saalbach, Gerhard, Crow, Allister, Kehoe, Michael A., Banfield, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962485/
https://ncbi.nlm.nih.gov/pubmed/20729215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149385
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