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Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium

The tumor suppressor p53 is a major regulator of genes important for cell cycle arrest, senescence, apoptosis and innate immunity, and has recently been implicated in retinal aging. In this study we sought to identify the genetic networks that regulate p53 function in the retina using quantitative t...

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Detalhes bibliográficos
Publicado no:Mamm Genome
Main Authors: Chaum, Edward, Winborn, Christina S., Bhattacharya, Sujoy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450138/
https://ncbi.nlm.nih.gov/pubmed/25963977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9568-9
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