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Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium

The tumor suppressor p53 is a major regulator of genes important for cell cycle arrest, senescence, apoptosis and innate immunity, and has recently been implicated in retinal aging. In this study we sought to identify the genetic networks that regulate p53 function in the retina using quantitative t...

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Bibliografiske detaljer
Udgivet i:Mamm Genome
Main Authors: Chaum, Edward, Winborn, Christina S., Bhattacharya, Sujoy
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450138/
https://ncbi.nlm.nih.gov/pubmed/25963977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9568-9
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