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Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid
Myeloperoxidase (MPO), lactoperoxidase (LPO) and eosinophil peroxidase (EPO) play a central role in oxidative damage in inflammatory disorders by utilizing hydrogen peroxide and halides/pseudo halides to generate the corresponding hypohalous acid. The catalytic sites of these enzymes contain a coval...
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| Publicado no: | J Inorg Biochem |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449957/ https://ncbi.nlm.nih.gov/pubmed/25193127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.06.018 |
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