Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid

Myeloperoxidase (MPO), lactoperoxidase (LPO) and eosinophil peroxidase (EPO) play a central role in oxidative damage in inflammatory disorders by utilizing hydrogen peroxide and halides/pseudo halides to generate the corresponding hypohalous acid. The catalytic sites of these enzymes contain a coval...

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Détails bibliographiques
Publié dans:J Inorg Biochem
Auteurs principaux: Abu-Soud, Husam M., Maitra, Dhiman, Shaeib, Faten, Khan, Sana, Byun, Jaeman, Abdulhamid, Ibrahim, Yang, Zhe, Saed, Ghassan M., Diamond, Michael P., Andreana, Peter R., Pennathur, Subramaniam
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449957/
https://ncbi.nlm.nih.gov/pubmed/25193127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.06.018
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