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The complex pathophysiology of acquired aplastic anaemia

Immune-mediated destruction of haematopoietic stem/progenitor cells (HSPCs) plays a central role in the pathophysiology of acquired aplastic anaemia (aAA). Dysregulated CD8(+) cytotoxic T cells, CD4(+) T cells including T helper type 1 (Th1), Th2, regulatory T cells and Th17 cells, natural killer (N...

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Dades bibliogràfiques
Publicat a:Clin Exp Immunol
Autors principals: Zeng, Y, Katsanis, E
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449765/
https://ncbi.nlm.nih.gov/pubmed/25683099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12605
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