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The complex pathophysiology of acquired aplastic anaemia
Immune-mediated destruction of haematopoietic stem/progenitor cells (HSPCs) plays a central role in the pathophysiology of acquired aplastic anaemia (aAA). Dysregulated CD8(+) cytotoxic T cells, CD4(+) T cells including T helper type 1 (Th1), Th2, regulatory T cells and Th17 cells, natural killer (N...
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| Veröffentlicht in: | Clin Exp Immunol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449765/ https://ncbi.nlm.nih.gov/pubmed/25683099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12605 |
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