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The complex pathophysiology of acquired aplastic anaemia

Immune-mediated destruction of haematopoietic stem/progenitor cells (HSPCs) plays a central role in the pathophysiology of acquired aplastic anaemia (aAA). Dysregulated CD8(+) cytotoxic T cells, CD4(+) T cells including T helper type 1 (Th1), Th2, regulatory T cells and Th17 cells, natural killer (N...

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Detalles Bibliográficos
Publicado en:Clin Exp Immunol
Autores principales: Zeng, Y, Katsanis, E
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449765/
https://ncbi.nlm.nih.gov/pubmed/25683099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12605
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