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RhoC and ROCKs regulate cancer cell interactions with endothelial cells

RhoC is a member of the Rho GTPase family that is implicated in cancer progression by stimulating cancer cell invasiveness. Here we report that RhoC regulates the interaction of cancer cells with vascular endothelial cells (ECs), a crucial step in the metastatic process. RhoC depletion by RNAi reduc...

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Bibliografski detalji
Izdano u:Mol Oncol
Glavni autori: Reymond, Nicolas, Im, Jae Hong, Garg, Ritu, Cox, Susan, Soyer, Magali, Riou, Philippe, Colomba, Audrey, Muschel, Ruth J., Ridley, Anne J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449123/
https://ncbi.nlm.nih.gov/pubmed/25677806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.01.004
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