RhoC and ROCKs regulate cancer cell interactions with endothelial cells

RhoC is a member of the Rho GTPase family that is implicated in cancer progression by stimulating cancer cell invasiveness. Here we report that RhoC regulates the interaction of cancer cells with vascular endothelial cells (ECs), a crucial step in the metastatic process. RhoC depletion by RNAi reduc...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Reymond, Nicolas, Im, Jae Hong, Garg, Ritu, Cox, Susan, Soyer, Magali, Riou, Philippe, Colomba, Audrey, Muschel, Ruth J., Ridley, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449123/
https://ncbi.nlm.nih.gov/pubmed/25677806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.01.004
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