Pharmacological effects of recombinant human tissue kallikrein on bradykinin B(2) receptors

Tissue kallikrein (KLK-1), a serine protease, initiates the release of bradykinin (BK)-related peptides from low-molecular weight kininogen. KLK-1 and the BK B(2) receptor (B(2)R) mediate beneficial effects on the progression of type 2 diabetes and renal disease, but the precise role of KLK-1 indepe...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Charest-Morin, Xavier, Raghavan, Arvind, Charles, Matthew L, Kolodka, Tadeusz, Bouthillier, Johanne, Jean, Mélissa, Robbins, Mark S, Marceau, François
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448978/
https://ncbi.nlm.nih.gov/pubmed/26038695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.119
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