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Expression Cloning and Regulation of Steroid 5α-Reductase, an Enzyme Essential for Male Sexual Differentiation

The conversion of testosterone into the more potent androgen, dihydrotestosterone, catalyzed by the enzyme steroid 5α-reductase, is required for the differentiation of male external genitalia. Here, we report the isolation of cDNA clones encoding the rat steroid 5α-reductase using expression cloning...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Andersson, Stefan, Bishop, Richard W., Russell, David W.
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448950/
https://ncbi.nlm.nih.gov/pubmed/2476440
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