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Unexpected Virilization in Male Mice Lacking Steroid 5α-Reductase Enzymes

Mice lacking steroid 5α-reductase 1 and 2 were produced by gene targeting and breeding. Male mice without 5α-reductase 2 or without both enzymes had fully formed internal and external genitalia and were fertile, but had smaller prostates and seminal vesicles than controls. T accumulated to high leve...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: MAHENDROO, MALA S., CALA, KRISTI M., HESS, DAVID L., RUSSELL, DAVID W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446976/
https://ncbi.nlm.nih.gov/pubmed/11606430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endo.142.11.8510
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