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Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism

The conversion of testosterone into dihydrotestosterone by steroid 5α-reductase is a key reaction in androgen action, and is essential both for the formation of the male phenotype during embryogenesis and for androgen-mediated growth of tissues such as the prostate(1,2). Single gene defects that imp...

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Publicat a:Nature
Autors principals: Andersson, Stefan, Berman, David M., Jenkins, Elizabeth P., Russell, David W.
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451825/
https://ncbi.nlm.nih.gov/pubmed/1944596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/354159a0
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