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Tumor homologous recombination deficiency assays: another step closer to clinical application?

Inherited and acquired defects in homologous recombination, a phenotype termed ‘BRCAness’, may lend to therapeutic exploitation in breast cancer. To this end, development and clinical evaluation of platforms to identify signatures of BRCAness are of immense interest. In this issue of Breast Cancer R...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Stecklein, Shane R, Sharma, Priyanka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448910/
https://ncbi.nlm.nih.gov/pubmed/25928813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0409-7
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