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Homologous Recombination Deficiency Testing for BRCA-Like Tumors: The Road to Clinical Validation
SIMPLE SUMMARY: Optimal cancer treatment requires the selection of patients based on the characteristics of their tumors. This review explores various strategies to select patients for DNA double strand break-inducing agents, such as PARP inhibitors. Patients with germline BRCA1/2 mutations benefit...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7957671/ https://ncbi.nlm.nih.gov/pubmed/33670893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051004 |
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