DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response

The immunocompetence and clinical accessibility of dermal tissue offers an appropriate and attractive target for vaccination. We previously demonstrated that pDNA injection into the skin in combination with surface electroporation (SEP), results in rapid and robust expression of the encoded antigen...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: Smith, Trevor RF, Schultheis, Katherine, Kiosses, William B, Amante, Dinah H, Mendoza, Janess M, Stone, John C, McCoy, Jay R, Sardesai, Niranjan Y, Broderick, Kate E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448738/
https://ncbi.nlm.nih.gov/pubmed/26052522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.54
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