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Genetic Modifiers and Oligogenic Inheritance

Despite remarkable progress in the identification of mutations that drive genetic disorders, progress in understanding the effect of genetic background on the penetrance and expressivity of causal alleles has been modest, in part because of the methodological challenges in identifying genetic modifi...

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Dades bibliogràfiques
Publicat a:Cold Spring Harb Perspect Med
Autors principals: Kousi, Maria, Katsanis, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448705/
https://ncbi.nlm.nih.gov/pubmed/26033081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017145
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