Oligogenic heterozygous inheritance of sperm abnormalities in mouse

Male infertility is an important health concern that is expected to have a major genetic etiology. Although high-throughput sequencing has linked gene defects to more than 50% of rare and severe sperm anomalies, less than 20% of common and moderate forms are explained. We hypothesized that this low...

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Detalhes bibliográficos
Main Authors: Guillaume Martinez, Charles Coutton, Corinne Loeuillet, Caroline Cazin, Jana Muroňová, Magalie Boguenet, Emeline Lambert, Magali Dhellemmes, Geneviève Chevalier, Jean-Pascal Hograindleur, Charline Vilpreux, Yasmine Neirijnck, Zine-Eddine Kherraf, Jessica Escoffier, Serge Nef, Pierre F Ray, Christophe Arnoult
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2022-04-01
Colecção:eLife
Assuntos:
infertility
oligogenism
heredity
sperm abnormalities
MMAF
Acesso em linha:https://elifesciences.org/articles/75373
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