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A pooling-based approach to mapping genetic variants associated with DNA methylation

DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to microarrays that cover <2% of the gen...

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Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Kaplow, Irene M., MacIsaac, Julia L., Mah, Sarah M., McEwen, Lisa M., Kobor, Michael S., Fraser, Hunter B.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448686/
https://ncbi.nlm.nih.gov/pubmed/25910490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.183749.114
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