Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

BACKGROUND: The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer’s Disease (AD). In addition, trisomies have been shown to disrupt normal ep...

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Detalhes bibliográficos
Main Authors: Jones, Meaghan J, Farré, Pau, McEwen, Lisa M, MacIsaac, Julia L, Watt, Kim, Neumann, Sarah M, Emberly, Eldon, Cynader, Max S, Virji-Babul, Naznin, Kobor, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879645/
https://ncbi.nlm.nih.gov/pubmed/24373378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-58
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