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A pooling-based approach to mapping genetic variants associated with DNA methylation

DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to microarrays that cover <2% of the gen...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Kaplow, Irene M., MacIsaac, Julia L., Mah, Sarah M., McEwen, Lisa M., Kobor, Michael S., Fraser, Hunter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448686/
https://ncbi.nlm.nih.gov/pubmed/25910490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.183749.114
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