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The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development
The chemokine CXCL12 and its receptor CXCR4 have many functions during embryonic and post-natal life. We used murine models to investigate the role of CXCL12/CXCR4 signaling in cardiac development and found that embryonic Cxcl12-null hearts lacked intra-ventricular coronary arteries (CAs) and exhibi...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448146/ https://ncbi.nlm.nih.gov/pubmed/26017770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.03.026 |
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