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Negative Regulation of Leptin-induced Reactive Oxygen Species (ROS) Formation by Cannabinoid CB(1) Receptor Activation in Hypothalamic Neurons

The adipocyte-derived, anorectic hormone leptin was recently shown to owe part of its regulatory effects on appetite-regulating hypothalamic neuropeptides to the elevation of reactive oxygen species (ROS) levels in arcuate nucleus (ARC) neurons. Leptin is also known to exert a negative regulation on...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Palomba, Letizia, Silvestri, Cristoforo, Imperatore, Roberta, Morello, Giovanna, Piscitelli, Fabiana, Martella, Andrea, Cristino, Luigia, Di Marzo, Vincenzo
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447947/
https://ncbi.nlm.nih.gov/pubmed/25869131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646885
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