Combination Treatment With Meropenem Plus Levofloxacin Is Synergistic Against Pseudomonas aeruginosa Infection in a Murine Model of Pneumonia

Background. Meropenem plus levofloxacin treatment was shown to be a promising combination in our in vitro hollow fiber infection model. We strove to validate this finding in a murine Pseudomonas pneumonia model. Methods. A dose-ranging study with meropenem and levofloxacin alone and in combination a...

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Vydáno v:J Infect Dis
Hlavní autoři: Louie, Arnold, Liu, Weiguo, VanGuilder, Michael, Neely, Michael N., Schumitzky, Alan, Jelliffe, Roger, Fikes, Steven, Kurhanewicz, Stephanie, Robbins, Nichole, Brown, David, Baluya, Dodge, Drusano, George L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447837/
https://ncbi.nlm.nih.gov/pubmed/25362196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu603
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