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Progressive Impairment of Lactate-based Gluconeogenesis in the Huntington’s Disease Mouse Model R6/2

Huntington’s disease (HD) is a neurodegenerative illness, where selective neuronal loss in the brain caused by expression of mutant huntingtin protein leads to motor dysfunction and cognitive decline in addition to peripheral metabolic changes. In this study we confirm our previous observation of im...

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Detalhes bibliográficos
Publicado no:PLoS Curr
Main Authors: Nielsen, Signe Marie Borch, Hasholt, Lis, Nørremølle, Anne, Josefsen, Knud
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447482/
https://ncbi.nlm.nih.gov/pubmed/26064782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.hd.019b33aae1c519e6e8b68e7cf3e7818e
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