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Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease

BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder linked to expanded CAG-triplet nucleotide repeats within the huntingtin gene. Intracellular huntingtin aggregates are present in neurons of distinct brain areas, among them regions of adult neurogenesis in...

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Detalhes bibliográficos
Main Authors: Kohl, Zacharias, Regensburger, Martin, Aigner, Robert, Kandasamy, Mahesh, Winner, Beate, Aigner, Ludwig, Winkler, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945356/
https://ncbi.nlm.nih.gov/pubmed/20836877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-114
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