The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

The Insulin/IGF-like signalling (IIS) pathway plays an evolutionarily conserved role in ageing. In model organisms reduced IIS extends lifespan and ameliorates some forms of functional senescence. However, little is known about IIS in nervous system ageing and behavioural senescence. To investigate...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Ismail, Mohd Zamri Bin Haji, Hodges, Matt D., Boylan, Michael, Achall, Rajesh, Shirras, Alan, Broughton, Susan J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447345/
https://ncbi.nlm.nih.gov/pubmed/26020640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125312
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